General Leveling Tips show
When in doubt. Life it out. There's an in-general rule of about 300 life per act that I try and follow to see if I'm "tanky enough" to do lab, boss, etc.
The game is balanced around having max (75) of each resistance at all points in the game. If you are getting one shot and you don't know why - this is the reason.
Gearing is as simple as picking up some life and resists. I'll mention where to get the powerful 2 resist recipes while leveling. If you're in softcore I don't mind being stingy with upgrades. I like saving currency for maps so I'll use essences as a free Orb of Alchemy.
Coloring gear is easy based on what the stat requirements of the item is. An item that requires more int is more inclined to have blue sockets. Dexterity Green. Strength Red. Getting colors not of the stat are considered "off color". This guide wants a ton of blue sockets and a couple green/red.
In general with Bane it is really easy to overlevel because killing and entire pack is as easy as just dropping a Bane and running through. With a good loot filter you can keep running to the map objective while killing.
Speaking of filters, I recommend getting Neversink's latest filter, I use Semi-Strict or Strict while leveling.
I don't pick up Scrolls of Wisdom. You can vendor Orbs of Transmutation or Blacksmith Whetstones for Scrolls of Wisdom.
Rememeber the guide is just a guideline - consider taking more defense (Mind Over Matter) earlier if in Hardcore. Dark Arts and/or Wither Totems if more experienced. This guide is aimed at newer players at a league start.

Act 1 - Target Tree show
Get Blight quest reward.
Equip 2 wands as soon as you can (for spell damage) implicits. Buy a 3 link Blue-Blue-Green if available. Also check the vendor for Movespeed boots. Keep a lookout for Blue Gems on Gloves/Helm as well to later socket in Flame Dash
Link Blight with Arcane Surge. If you happen to have a Blue-Blue-Blue Wand link it with Infused Channeling later.
Useful Tip - the vendors will reset their inventory after you level up!
Another tip for early levels is to not use a Body Armor for a little more movement speed. Body Armors have a hidden implicit of reduced movement speed!
Grab The Coast Waypoint and head to the Optional Tidal Island Quest to get a Quicksilver Flask. Leave your Arcane Surge level 1. To do this - Right Click it instead of Left Clicking it when the gem appears on the side). More on why you want to do this in 6. Tips and Tricks.
Go to the Submerged Passage and kill the Deep Dweller for a Skill Point. (grab Contagion as your quest reward)
Link Contagion with Arcane Surge as soon as you can. NOTE: Contagion may look weak but it lasts 5 seconds. The playstyle will be to cast a Contagion and run past the mobs to keep moving towards the next pack. Later on when you get Essence Drain that is used for tough rares but most of the time you should be skipping them when possible. Blight at this point is your supplemental single target.
Craft a +1 Chaos Gems Wand/Scepter if you have a Blue-Blue-Green magical wand (vendor a magial Wand with a Chaos Gem) - (You can buy a Blight gem from Nessa for 1 scroll of wisdom)https://pathofexile.gamepedia.com/Vendor_recipe_system#Crafting
Make sure you do your Trial of Ascendancy in the Lower Prison.
Kill Brutus and grab Flame Dash and Void Manipulation. After you equip Flame Dash click on it in your bar and select the checkbox for "Always Attack Without Moving".
If you were lucky enough to get a Blue-Blue-Green it should be Contagion - Void Manipulation - Arcane Surge
Grab the waypoint in the Ship Graveyard and find the All Flame and return it to Fairgraves there.
Return to town once you reach the Cavern of Wrath and grab Essence Drain (doesn't need any extra links it's supplemental single target). An additional supplemental single target setup is Spell Totem - Wither This is not necessary and the colors may be a pain. Consider upgrading to the highest life/mana flasks from Nessa. Kill the Act Boss

Act 2 - Target Tree show
Keep a lookout for gear with Dexterity (generally an amulet) and still look for more Blue sockets.
Head right to the Old Fields and then to the Den to get your second Quicksilver Flask.
Keep heading right and Kill Kraityn.
Back to the Crossroads and head down to get the next Trial of Ascendancy in The Crypt Level 1.
Head left from town into The Riverways grab the waypoint and head up into The Wetlands.
Kill Oak and grab the waypoint in the Wetlands. Go back to the Riverways and head left to the Western Forest. 3 quests to do here 1) Kill Alira 2) The Way Forward (Thaumetic Emblem/Seal) 3) Weavers Chambers.
After killing the weaver get Controlled Destruction. You can also buy a Faster Casting for the supplemental Wither Totem setup I mentioned in act 1. Begin leveling it on an extra blue slot (maybe in your weapon swap). Once you get a 4-link you'll want to use this with your Contagion/Bane.
Head back to the Crossroads after doing all 3 quests in the Western Forest and head north.
Make sure you do your Trial of Ascendancy in the Chamber of Sins Level 2.
Head back to the Wetlands and open the entrance to the Vaal Ruins. Run through the Vaal Ruins and the Northern Forest to The Caverns (don't enter the Dread Thicket!). Run through The Caverns.
Consider upgrading to the highest life/mana flasks from Yeena. Kill the boss and make sure to grab the spell damage recipe in the room to the left.

Act 3 - Target Tree show
In act 3 look out for a 4-link that's Blue-Blue-Blue-Green. If you get a 4 link it should be Bane - Despair - Controlled Destruction - Void Manipulation if you get 4 Blue then consider using Arcane Surge until you can color it or find a green socket.
Head out of the sewers and hug the sides to enter to Crematorium. Make sure you do your Trial of Ascendancy here. Kill Piety and head back to town.
Grab Bane and buy Despair off of Clarissa. Also Grab Malevolence and begin using it as your only aura.
Grab the Keys from Clarissa and head to the Sewers. Grab the 3 Platinum Busts in the Sewer.
Run through The Marketplace and head to The Catacombs for your 5th Trial of Ascendancy.
After the trial head back to the marketplace and run through to the battlefront. Find the waypoint, head to the left of the waypoint to grab the quest item and head north to the docks.
At the docks there are two things to do: 1) Find the Sulphite 2) Talk to Fairgraves and grab the waypoint.
Head back to the battlefront. Head north again but to the east of the docks to get to the Solaris Temple.
Run through Solaris and talk to Dalia. Turn in your quests - grab the dex Amulet reward if you need the dex.
Head to the sewer and run to the left. Run through the ebony Barracks to the northwest. Kill Gravicious and head west to the Lunaris Temple.
Run through the Lunaris Temple level 2 and kill Piety for the Tower Key. The gem you get from Maroma does not matter.
Back to The Ebony Barracks and head east to the Imperial Gardens. Grab the waypoint head to the north west and do your last Trial of Ascendancy there!
Optional quest to do the Library to pick up Efficacy Support and Swift Affliction these will be great DPS gems for your final setup. If you don't want to do it now, you can wait until act 6 to grab them off Lily
Do your Lab. Update your flasks to the highest you can equip. Consider rolling a bleed removal flask. Ascend into Occultist.
Head back to the Imperial Gardens and go east to the Upper Scepter of God. Kill Dominus and proceed to act 4

Act 4 - Target Tree show
Enter the town and go left to the Dried Lake. Kill Voll (and get the attack/cast speed crafting recipe) and head to the mine after.
Consider doing your first Delve after hitting sulphite to get the 2-3 Socket Recipe from the first Delve Node
in the mines level 2 take the extra time to find the Deshrets Spirit for a Skill Point before heading to the next level, Keep an eye out for any Blue-Blue-Blue-Green items or heavy int based items that you can use a chrome on to get 3 blue 1 green. (Items which require more Intelligence are predisposed to getting Blue sockets. Dexterity Green. Strength Red.
In the Crystal Veins grab the waypoint and go do either of the side areas. talk to Oyun and grab a Chaos Golem.
Head back to the Crystal Veins and head to the two side areas to kill the respective bosses of the area and grab the quest items from them.
Make your way through the Belly of the Beast and kill Piety. Kill all the mini bosses and harvest their organs.
Before the boss fight - update your flasks, turn in quest rewards. I like grabbing Multiple Totems for the supplemental Wither Totem setup. The supplemental wither totem setup could look like this at this point if you have the links: Spell Totem - Multiple Totems Support - Wither - Faster Casting
Kill Malachai and proceed to Act 5

Act 5 - Target Tree show
After this act you'll be losing 30 resist.
Run through the Slave Pens (hugging the left) and kill the overseer to head into the Overseer's Tower.
Head through the Control Blocks and grab the Miasmeter on the way to Oriath Square (red X's on the ground let you know you're heading the right direction.
Run north east/east to the Templar Courts return to town to get an Onslaught Flask (I replace 1 quicksilver and press both Onslaught and Quicksilver together for more movement speed). Head back to Templar Courts and run in a clockwise circle to The Chamber of Innocence.
Run in a counter clockwise circle to kill the boss (grab the movement speed recipe on the way).
Head back through the Torched Courts after the fight to the Ruined Square. Here grab the Reliquary items to the south of the Square and the Sign of Purity in The Ossuary.
Head to town - update your flasks turn in your quest rewards (nothing important other than skill points). Head to The Cathedral Rooftop to kill Kitava. You will suffer a permanent -30 resist penalty. Consider crafting better gear with essences or using the crafting bench where you have open suffixes. This is a good time to learn about Item Affixes and what a Prefix vs Suffix is: https://pathofexile.gamepedia.com/Item_affix

Act 6 - Target Tree show
Head to the left in town and clear the Twilight Strand. This will allow you to buy any skill gem from Lily!
At this point I buy Cast When Damage Taken - Immortal Call and (in SSF I LOVE Increased Item Rarity support if I'm doing okay on damage and can sacrifice a link)
Also grab a Swift Affliction and replace Void Manipulation in your main setup. (continue to level Void Manipulation if you have a free green socket somewhere. Grab an Efficacy Support to start leveling as well.
If you have a Red-Red then link Cast When Damage Taken and Immortal Call together. Leave them low level (explanation of why in 3. Gems and Links)
Run through The Coast and head to the Mud Flats (there's an Optional quest in the Tidal Island if you're looking for an amulet or belt upgrade).
In the Mud Flats kill the Queen to the east and head to the Karui Fortress in the North.
Kill Tukohama and talk to Sin to grab your first Pantheon Power.
Head to the Ridge, run through to the Lower Prison and begin your next set of Trial of Ascendancy (grab the double resistances recipe!)
Head up through the tower and kill the boss. Grab your quest reward and consider a 4 link that you might need.
Head to the Prisoner's Gate and kill Abberath for a Skill Point. Head into the Western Forest and The Riverways and get the waypoint there. Head north to kill The Puppet Mistress for a Skill Point (I like talking to Sin after this fight to switch into Soul of Ryslatha Pantheon). Head back to The Riverways and head east to the Southern Forest.
Run through the Cavern of Anger. Head to the Beacon (grab the life and mana crafting recipe there) throw the flag into the lit Beacon and head to The Brine King's Reef.
As usual - head to town and upgrade your flasks. Having capped cold resistance for this fight is nice. Talk to Sin after killing the Brine King for your first Major Pantheon.

Act 7 - Target Tree show
Head into the Broken Bridge and do the Optional Silver Locket quest to grab a Sulphur Flask. I replace one of my Life Flasks with the Sulphur Flask.
Sulphur Flasks increase your damage and create consecrated ground.
Grab the waypoint in the Crossroads. Head south to the Fellshine Ruins and do your Trial of Ascendancy in the Crypt. Afterwards grab Maligaro's Map.
Head back to the Crossroads and head north into the Chamber of Sins. In the Chamber of Sin's place the map into the Map Device and enter Maligaro's Sanctum. Kill Maligaro and head to the Chamber of Sins Level 2. Do your Trial of Ascendancy here.
After this Trial you now have the ability to do your Cruel Lab.
After running through the Chamber of Sins and The Den. Go west in The Ashen Fields to kill Greust.
In the Northern Forest there are many quests to do 1) Head into the Dread Thicket and kill Gruthkul. 2) Also while in the Dread Thicket, collect the fireflies. 3) Optional In Memory of Greust quest for an amulet (it's on the way, and is a free rare amulet - I always do this one)
Head to the Causeway run through and grab the Kishara's Star for a Skill Point and then enter Vaal City. Upgrade your flasks. Run through to the act boss and kill Arakaali for

Act 8 - Target Tree show
I do my Cruel Lab immediately upon entering Act 8. In this lab you'll get rank 2 double resistances.
Head back to town - head to the left and make your way through the sewers to Doedre's Cesspool. Kill Doedre and grab the waypoint and Level 3 resistances recipe outside.
You can technically do either of the sides first - I like doing Solar before Lunar (head right from the waypoint).
In the Quay hug the edges to look for a skinny bridge to pick up the Ankh of Eternity. Help Clarissa with the Ankh for a Skill Point. Grab the Grain Gate waypoint if you see it before you meet Clarissa.
In the Grain Gate kill the Gemling Legion for a Skill Point (if you get lost in the Grain Gate follow the doors with dead bodies in front of them) and proceed to the Imperial Fields. Run through the fields and the Solaris Temple. If you see a door for Solaris Concourse do not take it. Head to the Solaris Temple Level 2 and kill the boss for the Sun Orb.
Head back to the Toxic Conduits and go left this time. Run through the Grand Promenade and head to The Bath House. There three things to do in here 1) Optional Wings of Vastiri (he sits in the middle of the map so you'll end up doing him anyway. 2) Trial of Ascendancy (also grab the flask duration recipe inside) 3) The High Gardens for a Skill Point Quest.
Proceed to the Lunaris Concourse and grab the waypoint. Head north of the waypoint to the Lunaris Temple and proceed to Level 2 and kill the boss for the Moon Orb.
Head back to the Lunaris Concourse waypoint and head south to the Harbor Bridge. Kill the Act bosses and Proceed to Act 9.

Act 9 - Target Tree show
Blood Aquaducts is a very popular farming location because of Humility Divination Cards. Consider staying here and leveling for a while and gearing up. It's also a level 60+ Zone for those doing the Chaos Recipe.
Once in Highgate head right into The Decent and progress down into The Vastiri Desert where you'll be looking for the waypoint and the Storm Blade quest. There is an Attack and Cast Speed recipe by the waypoint as well.
Turn in the Storm Blade quest to Petarus and Vanja, talk to Sin, and talk to Petarus and Vanja again for the Bottled Cloud. Head back to The Vastiri Desert and head North East into the Oasis for another Skill Point Quest.
Head to the north west of The Vastiri Desert for The Foothills - grab the waypoint there. Head east of the waypoint for The Basilisk Acid (make sure to grab the Spell Damage level 3 behind the boss!)
Go back to The Foothills waypoint head west for The Tunnel. Do your Trial of Ascendancy (and grab the All Attributes rank 2 recipe). Proceed to The Quarry and grab the waypoint. Hug the sides to find the Trarthan Powder (The Refinery) and Save Oyun from Kira (Shrine of the Winds).
Head back to The Quarry. Talk to Sin and proceed to The Belly of the Beast. Run through The Belly The Rotting Core and Kill all three bosses, Kill the final act boss and Proceed to Act 10.

Act 10 - Target Tree show
Head to the rooftop to Rescue Bannon. Head East in the Rooftop hugging the sides to get to The Ravaged Square. Hug the wall along the west to head into the Control Blocks and kill Vilenta for a Skill Point.
Head back to the Control Blocks waypoint but head out to the Ravaged Square and proceed north east to hit the waypoint. Head into the Ossuary for your Trial of Ascendancy. You can now do your Merciless Lab.
In Merciless Lab you get rank 3 double resistances!
Head east of The Ravaged Square waypoint to The Desecrated Chambers and kill Avarius.
Kill Kitava (you will suffer a permanent -30 resist penalty after this fight)
Head to the North in the Epilogue to get the Movement Speed rank 3 craft.
Check to see if you missed any passive points by typing /passives
Head into the Templar Laboratory to the east and grab maps from Zana - Welcome to the Endgame!

Endgame and Beyond - Final Skill Tree show
Begin progressing through maps tier by tier. Buy maps that you don't have if you're in a trade league.
I like picking up Mind over Matter and Phase Acrobatics to get defense as soon as possible.
Begin getting upgrades for your gear.
Readers paying attention may notice that my final skill tree ends at level 86 and doesn't include anything for using a Shield, Staff, or Dual Wielding